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Long non-coding RNA SLC2A1-AS1 induced by GLI3 promotes aerobic glycolysis and progression in esophageal squamous cell carcinoma by sponging miR-378a-3p to enhance Glut1 expression

BACKGROUND: Emerging evidence demonstrates that lncRNAs play pivotal roles in tumor energy metabolism; however, the detailed mechanisms of lncRNAs in the regulation of tumor glycolysis remain largely unknown. METHODS: The expression of SLC2A1-AS1 was investigated by TCGA, GEO dataset and qRT-PCR. Th...

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Detalles Bibliográficos
Autores principales: Liu, Hongtao, Zhang, Qing, Song, Yinsen, Hao, Yibin, Cui, Yunxia, Zhang, Xin, Zhang, Xueying, Qin, Yue, Zhu, Guangzhao, Wang, Feng, Dang, Jinghan, Ma, Shanshan, Zhang, Yanting, Guo, Wenna, Li, Shenglei, Guan, Fangxia, Fan, Tianli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436487/
https://www.ncbi.nlm.nih.gov/pubmed/34517880
http://dx.doi.org/10.1186/s13046-021-02081-8