Randomised, double-blind comparison of a fixed co-formulation of intra-articular polynucleotides and hyaluronic acid versus hyaluronic acid alone in the treatment of knee osteoarthritis: two-year follow-up

BACKGROUND: A first-year interim analysis of this two-year study suggested that intra-articular injections of highly purified, natural-origin polynucleotides and hyaluronic acid (HA) as a fixed combination (PNHA) might improve knee function and joint pain more effectively than HA alone in patients w...

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Detalles Bibliográficos
Autores principales: Stagni, Cesare, Rocchi, Martina, Mazzotta, Alessandro, Del Piccolo, Nicolandrea, Rani, Nicola, Govoni, Marco, Vivarelli, Leonardo, Veronesi, Francesca, Fini, Milena, Dallari, Dante
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436495/
https://www.ncbi.nlm.nih.gov/pubmed/34511091
http://dx.doi.org/10.1186/s12891-021-04648-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436495/
https://www.ncbi.nlm.nih.gov/pubmed/34511091
http://dx.doi.org/10.1186/s12891-021-04648-0

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