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Randomised, double-blind comparison of a fixed co-formulation of intra-articular polynucleotides and hyaluronic acid versus hyaluronic acid alone in the treatment of knee osteoarthritis: two-year follow-up
BACKGROUND: A first-year interim analysis of this two-year study suggested that intra-articular injections of highly purified, natural-origin polynucleotides and hyaluronic acid (HA) as a fixed combination (PNHA) might improve knee function and joint pain more effectively than HA alone in patients w...
Autores principales: | Stagni, Cesare, Rocchi, Martina, Mazzotta, Alessandro, Del Piccolo, Nicolandrea, Rani, Nicola, Govoni, Marco, Vivarelli, Leonardo, Veronesi, Francesca, Fini, Milena, Dallari, Dante |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436495/ https://www.ncbi.nlm.nih.gov/pubmed/34511091 http://dx.doi.org/10.1186/s12891-021-04648-0 |
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