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Brain profiling in murine colitis and human epilepsy reveals neutrophils and TNFα as mediators of neuronal hyperexcitability

BACKGROUND: Patients with chronic inflammatory disorders such as inflammatory bowel disease frequently experience neurological complications including epilepsy, depression, attention deficit disorders, migraines, and dementia. However, the mechanistic basis for these associations is unknown. Given t...

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Detalles Bibliográficos
Autores principales: Barnes, Sarah E., Zera, Kristy A., Ivison, Geoffrey T., Buckwalter, Marion S., Engleman, Edgar G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436533/
https://www.ncbi.nlm.nih.gov/pubmed/34511110
http://dx.doi.org/10.1186/s12974-021-02262-4