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Knockdown of POLQ interferes the development and progression of hepatocellular carcinoma through regulating cell proliferation, apoptosis and migration

BACKGROUND: DNA Polymerase Theta (POLQ) is a DNA polymerase involved in error-prone translesion DNA synthesis (TLS) and error-prone repair of DNA double-strand breaks (DSBs), whose function in hepatocellular carcinoma has not been investigated. METHODS: In the present study, both the data collected...

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Detalles Bibliográficos
Autores principales: Pan, Qi, Wang, Lu, Liu, Yu, Li, Min, Zhang, Yao, Peng, Wei, Deng, Tan, Peng, Mei-Ling, Jiang, Jin-Qiong, Tang, Jiao, Wang, Jingjing, Duan, Hua-Xin, Fan, Sha-Sha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436534/
https://www.ncbi.nlm.nih.gov/pubmed/34517891
http://dx.doi.org/10.1186/s12935-021-02178-2