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Modulation of endothelial organelle size as an antithrombotic strategy

BACKGROUND: It is long established that von Willebrand factor (VWF) is central to hemostasis and thrombosis. Endothelial VWF is stored in cell‐specific secretory granules, Weibel‐Palade bodies (WPBs), organelles generated in a wide range of lengths (0.5‐5.0 µm). WPB size responds to physiological cu...

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Detalles Bibliográficos
Autores principales: Ferraro, Francesco, Patella, Francesca, Costa, Joana R., Ketteler, Robin, Kriston‐Vizi, Janos, Cutler, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436738/
https://www.ncbi.nlm.nih.gov/pubmed/32881285
http://dx.doi.org/10.1111/jth.15084