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Modulation of endothelial organelle size as an antithrombotic strategy
BACKGROUND: It is long established that von Willebrand factor (VWF) is central to hemostasis and thrombosis. Endothelial VWF is stored in cell‐specific secretory granules, Weibel‐Palade bodies (WPBs), organelles generated in a wide range of lengths (0.5‐5.0 µm). WPB size responds to physiological cu...
Autores principales: | Ferraro, Francesco, Patella, Francesca, Costa, Joana R., Ketteler, Robin, Kriston‐Vizi, Janos, Cutler, Daniel F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436738/ https://www.ncbi.nlm.nih.gov/pubmed/32881285 http://dx.doi.org/10.1111/jth.15084 |
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