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Physiologic osteoclasts are not sufficient to induce skeletal pain in mice

BACKGROUND: Increased bone resorption is driven by augmented osteoclast activity in pathological states of the bone, including osteoporosis, fracture and metastatic bone cancer. Pain is a frequent co‐morbidity in bone pathologies and adequate pain management is necessary for symptomatic relief. Bone...

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Detalles Bibliográficos
Autores principales: de Clauser, Larissa, Santana‐Varela, Sonia, Wood, John N, Sikandar, Shafaq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436750/
https://www.ncbi.nlm.nih.gov/pubmed/32955748
http://dx.doi.org/10.1002/ejp.1662