Regulation of glycine metabolism by the glycine cleavage system and conjugation pathway in mouse models of non‐ketotic hyperglycinemia

Glycine abundance is modulated in a tissue‐specific manner by use in biosynthetic reactions, catabolism by the glycine cleavage system (GCS), and excretion via glycine conjugation. Dysregulation of glycine metabolism is associated with multiple disorders including epilepsy, developmental delay, and...

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Detalles Bibliográficos
Autores principales: Leung, Kit‐Yi, De Castro, Sandra C. P., Santos, Chloe, Savery, Dawn, Prunty, Helen, Gold‐Diaz, Diana, Bennett, Stuart, Heales, Simon, Copp, Andrew J., Greene, Nicholas D. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436753/
https://www.ncbi.nlm.nih.gov/pubmed/32743799
http://dx.doi.org/10.1002/jimd.12295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436753/
https://www.ncbi.nlm.nih.gov/pubmed/32743799
http://dx.doi.org/10.1002/jimd.12295

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