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Fluorescence lifetime imaging reveals regulation of presynaptic Ca(2+) by glutamate uptake and mGluRs, but not somatic voltage in cortical neurons
ABSTRACT: Brain function relies on vesicular release of neurotransmitters at chemical synapses. The release probability depends on action potential‐evoked presynaptic Ca(2+) entry, but also on the resting Ca(2+) level. Whether these basic aspects of presynaptic calcium homeostasis show any consisten...
Autores principales: | Tyurikova, Olga, Zheng, Kaiyu, Nicholson, Elizabeth, Timofeeva, Yulia, Semyanov, Alexey, Volynski, Kirill E., Rusakov, Dmitri A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436763/ https://www.ncbi.nlm.nih.gov/pubmed/32418206 http://dx.doi.org/10.1111/jnc.15094 |
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