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Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca(2+)-Activin A circuit in chronic cerebral hypoperfusion rats

Chronic cerebral ischemia (CCI) is one of the critical factors in the occurrence and development of vascular cognitive impairment (VCI). Apoptosis of nerve cells and changes in synaptic activity after CCI are the key factors to induce VCI. Synaptic stimulation up-regulates intraneuronal Ca(2+) level...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Shi, Xiaohua, Wang, Jiaoqi, Xu, Zhongxin, He, Jinting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436900/
https://www.ncbi.nlm.nih.gov/pubmed/34462377
http://dx.doi.org/10.18632/aging.203462