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Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca(2+)-Activin A circuit in chronic cerebral hypoperfusion rats
Chronic cerebral ischemia (CCI) is one of the critical factors in the occurrence and development of vascular cognitive impairment (VCI). Apoptosis of nerve cells and changes in synaptic activity after CCI are the key factors to induce VCI. Synaptic stimulation up-regulates intraneuronal Ca(2+) level...
Autores principales: | Zhang, Xin, Shi, Xiaohua, Wang, Jiaoqi, Xu, Zhongxin, He, Jinting |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436900/ https://www.ncbi.nlm.nih.gov/pubmed/34462377 http://dx.doi.org/10.18632/aging.203462 |
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