NF-κB inducible miR-30b-5p aggravates joint pain and loss of articular cartilage via targeting SIRT1-FoxO3a-mediated NLRP3 inflammasome

MicroRNAs (miRNAs) contribute to osteoarthritis (OA) development. Nevertheless, the function and mechanism of miR-30b-5p in OA are unclear. In the present article, we gauged the miR-30b-5p level in OA patients and analyzed its correlation with OA stages. Then, we conducted in-vivo and in-vitro gain-...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Haiting, Zhang, Jie, Shi, Xiaoming, Li, Xiaoyang, Zheng, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436920/
https://www.ncbi.nlm.nih.gov/pubmed/34455406
http://dx.doi.org/10.18632/aging.203466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436920/
https://www.ncbi.nlm.nih.gov/pubmed/34455406
http://dx.doi.org/10.18632/aging.203466

Ejemplares similares