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Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway

CONTEXT: The effect of kaempferol, a regulator of oestrogen receptors, on atherosclerosis (AS) and the underlying mechanism is elusive. OBJECTIVE: To explore the effect and mechanism of kaempferol on AS. METHODS AND MATERIALS: In vivo, C57BL/6 and apolipoprotein E (APOE)(–/–) mice were randomly cate...

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Detalles Bibliográficos
Autores principales: Feng, Zhuo, Wang, Changyuan, Jin, Yue, Meng, Qiang, Wu, Jingjing, Sun, Huijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436971/
https://www.ncbi.nlm.nih.gov/pubmed/34403325
http://dx.doi.org/10.1080/13880209.2021.1961823