Relationship Between Thiopurine S-Methyltransferase Genotype/Phenotype and 6-Thioguanine Nucleotide Levels in 316 Patients With Inflammatory Bowel Disease on 6-Thioguanine

In inflammatory bowel disease (IBD), conventional thiopurine users cease treatment in 60% of cases within 5 years, mostly because of adverse events or nonresponse. In this study, the authors aimed to investigate the role of 6-thioguanine nucleotide (TGN) measurements, geno/phenotyping of thiopurine...

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Detalles Bibliográficos
Autores principales: Bayoumy, Ahmed B., Mulder, Chris J. J., Loganayagam, Aathavan, Sanderson, Jeremy D., Anderson, Simon, Boekema, Paul J., Derijks, Luc J. J., Ansari, Azhar R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Therapeutic Drug Monitoring 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437045/
https://www.ncbi.nlm.nih.gov/pubmed/34521801
http://dx.doi.org/10.1097/FTD.0000000000000869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437045/
https://www.ncbi.nlm.nih.gov/pubmed/34521801
http://dx.doi.org/10.1097/FTD.0000000000000869

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