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Macrophage migration inhibitory factor (MIF) inhibitor 4-IPP downregulates stemness phenotype and mesenchymal trans-differentiation after irradiation in glioblastoma multiforme

Radiation therapy is among the most essential treatment methods for glioblastoma multiforme (GBM). Radio-resistance and cancer stem cell properties can cause therapeutic resistance, cancer heterogeneity, and poor prognoses in association with GBM. Furthermore, the GBM subtype transition from proneur...

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Detalles Bibliográficos
Autores principales: Lee, Shin Heon, Kwon, Hyung Joon, Park, Saewhan, Kim, Chan Il, Ryu, Haseo, Kim, Sung Soo, Park, Jong Bae, Kwon, Jeong Taik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437287/
https://www.ncbi.nlm.nih.gov/pubmed/34516577
http://dx.doi.org/10.1371/journal.pone.0257375