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IUSMMT: Survival mediation analysis of gene expression with multiple DNA methylation exposures and its application to cancers of TCGA

Effective and powerful survival mediation models are currently lacking. To partly fill such knowledge gap, we particularly focus on the mediation analysis that includes multiple DNA methylations acting as exposures, one gene expression as the mediator and one survival time as the outcome. We propose...

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Detalles Bibliográficos
Autores principales: Shao, Zhonghe, Wang, Ting, Zhang, Meng, Jiang, Zhou, Huang, Shuiping, Zeng, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437300/
https://www.ncbi.nlm.nih.gov/pubmed/34464378
http://dx.doi.org/10.1371/journal.pcbi.1009250