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IUSMMT: Survival mediation analysis of gene expression with multiple DNA methylation exposures and its application to cancers of TCGA
Effective and powerful survival mediation models are currently lacking. To partly fill such knowledge gap, we particularly focus on the mediation analysis that includes multiple DNA methylations acting as exposures, one gene expression as the mediator and one survival time as the outcome. We propose...
Autores principales: | Shao, Zhonghe, Wang, Ting, Zhang, Meng, Jiang, Zhou, Huang, Shuiping, Zeng, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437300/ https://www.ncbi.nlm.nih.gov/pubmed/34464378 http://dx.doi.org/10.1371/journal.pcbi.1009250 |
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