Streptococcus pneumoniae Binds to Host Lactate Dehydrogenase via PspA and PspC To Enhance Virulence

Pneumococcal surface protein A (PspA) and pneumococcal surface protein C (PspC, also called CbpA) are major virulence factors of Streptococcus pneumoniae (Spn). These surface-exposed choline-binding proteins (CBPs) function independently to inhibit opsonization, neutralize antimicrobial factors, or...

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Detalles Bibliográficos
Autores principales: Park, Sang-Sang, Gonzalez-Juarbe, Norberto, Martínez, Eriel, Hale, Joanetha Yvette, Lin, Yi-Han, Huffines, Joshua T., Kruckow, Katherine L., Briles, David E., Orihuela, Carlos J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437407/
https://www.ncbi.nlm.nih.gov/pubmed/33947761
http://dx.doi.org/10.1128/mBio.00673-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437407/
https://www.ncbi.nlm.nih.gov/pubmed/33947761
http://dx.doi.org/10.1128/mBio.00673-21

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