Cargando…

Hsp40s play complementary roles in the prevention of tau amyloid formation

The microtubule-associated protein, tau, is the major subunit of neurofibrillary tangles associated with neurodegenerative conditions, such as Alzheimer's disease. In the cell, however, tau aggregation can be prevented by a class of proteins known as molecular chaperones. While numerous chapero...

Descripción completa

Detalles Bibliográficos
Autores principales: Irwin, Rose, Faust, Ofrah, Petrovic, Ivana, Wolf, Sharon Grayer, Hofmann, Hagen, Rosenzweig, Rina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437434/
https://www.ncbi.nlm.nih.gov/pubmed/34369377
http://dx.doi.org/10.7554/eLife.69601