Identification of abscission checkpoint bodies as structures that regulate ESCRT factors to control abscission timing

The abscission checkpoint regulates the ESCRT membrane fission machinery and thereby delays cytokinetic abscission to protect genomic integrity in response to residual mitotic errors. The checkpoint is maintained by Aurora B kinase, which phosphorylates multiple targets, including CHMP4C, a regulato...

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Detalles Bibliográficos
Autores principales: Strohacker, Lauren K, Mackay, Douglas R, Whitney, Madeline A, Couldwell, Genevieve C, Sundquist, Wesley I, Ullman, Katharine S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437436/
https://www.ncbi.nlm.nih.gov/pubmed/34346309
http://dx.doi.org/10.7554/eLife.63743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437436/
https://www.ncbi.nlm.nih.gov/pubmed/34346309
http://dx.doi.org/10.7554/eLife.63743

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