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The amyloid precursor protein is a conserved Wnt receptor

The Amyloid Precursor Protein (APP) and its homologues are transmembrane proteins required for various aspects of neuronal development and activity, whose molecular function is unknown. Specifically, it is unclear whether APP acts as a receptor, and if so what its ligand(s) may be. We show that APP...

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Detalles Bibliográficos
Autores principales: Liu, Tengyuan, Zhang, Tingting, Nicolas, Maya, Boussicault, Lydie, Rice, Heather, Soldano, Alessia, Claeys, Annelies, Petrova, Iveta, Fradkin, Lee, De Strooper, Bart, Potier, Marie-Claude, Hassan, Bassem A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437438/
https://www.ncbi.nlm.nih.gov/pubmed/34515635
http://dx.doi.org/10.7554/eLife.69199