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Monoacylglycerol lipase deficiency in the tumor microenvironment slows tumor growth in non-small cell lung cancer

Monoacylglycerol lipase (MGL) expressed in cancer cells influences cancer pathogenesis but the role of MGL in the tumor microenvironment (TME) is less known. Using a syngeneic tumor model with KP cells (Kras(LSL-G12D)/p53(fl/fl); from mouse lung adenocarcinoma), we investigated whether TME-expressed...

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Detalles Bibliográficos
Autores principales: Kienzl, Melanie, Hasenoehrl, Carina, Maitz, Kathrin, Sarsembayeva, Arailym, Taschler, Ulrike, Valadez-Cosmes, Paulina, Kindler, Oliver, Ristic, Dusica, Raftopoulou, Sofia, Santiso, Ana, Bärnthaler, Thomas, Brcic, Luka, Hahnefeld, Lisa, Gurke, Robert, Thomas, Dominique, Geisslinger, Gerd, Kargl, Julia, Schicho, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437460/
https://www.ncbi.nlm.nih.gov/pubmed/34527428
http://dx.doi.org/10.1080/2162402X.2021.1965319