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Displaying epitope B and epitope 7 of porcine reproductive and respiratory syndrome virus on virus like particles of porcine circovirus type 2 provides partial protection to pigs

The Cap of porcine circovirus type 2 (PCV2) can be assembled into virus like particles (VLPs) in vitro that have multiple loops located on the particle surface. This would make it a good vehicle for displaying exogenous proteins or epitopes. We derived two epitopes, epitope B (EpB, S(37)HIQLIYNL(45)...

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Detalles Bibliográficos
Autores principales: LI, Guopan, LIU, Lei, XU, Baojuan, HU, Jixiong, KUANG, Hongyan, WANG, Xi, WANG, Liping, CUI, Xiaoxia, SUN, Houmin, RONG, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437722/
https://www.ncbi.nlm.nih.gov/pubmed/34234054
http://dx.doi.org/10.1292/jvms.21-0543