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The use of an in-vitro batch fermentation (human colon) model for investigating mechanisms of TMA production from choline, l-carnitine and related precursors by the human gut microbiota

PURPOSE: Plasma trimethylamine-N-oxide (TMAO) levels have been shown to correlate with increased risk of metabolic diseases including cardiovascular diseases. TMAO exposure predominantly occurs as a consequence of gut microbiota-dependent trimethylamine (TMA) production from dietary substrates inclu...

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Detalles Bibliográficos
Autores principales: Day-Walsh, Priscilla, Shehata, Emad, Saha, Shikha, Savva, George M., Nemeckova, Barbora, Speranza, Jasmine, Kellingray, Lee, Narbad, Arjan, Kroon, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437865/
https://www.ncbi.nlm.nih.gov/pubmed/33934200
http://dx.doi.org/10.1007/s00394-021-02572-6