Cargando…

The use of an in-vitro batch fermentation (human colon) model for investigating mechanisms of TMA production from choline, l-carnitine and related precursors by the human gut microbiota

PURPOSE: Plasma trimethylamine-N-oxide (TMAO) levels have been shown to correlate with increased risk of metabolic diseases including cardiovascular diseases. TMAO exposure predominantly occurs as a consequence of gut microbiota-dependent trimethylamine (TMA) production from dietary substrates inclu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Day-Walsh, Priscilla, Shehata, Emad, Saha, Shikha, Savva, George M., Nemeckova, Barbora, Speranza, Jasmine, Kellingray, Lee, Narbad, Arjan, Kroon, Paul A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Original Contribution
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437865/ https://www.ncbi.nlm.nih.gov/pubmed/33934200 http://dx.doi.org/10.1007/s00394-021-02572-6

Ejemplares similares

Intelligence-Aware Batch Processing for TMA with Bearings-Only Measurements
por: Oliva, Gabriele, et al.
Publicado: (2021)

Development and Validation of a LC-MS/MS Technique for the Analysis of Short Chain Fatty Acids in Tissues and Biological Fluids without Derivatisation Using Isotope Labelled Internal Standards
por: Saha, Shikha, et al.
Publicado: (2021)

Effects of in vitro metabolism of a broccoli leachate, glucosinolates and S-methylcysteine sulphoxide on the human faecal microbiome
por: Kellingray, Lee, et al.
Publicado: (2020)

Consumption of a diet rich in Brassica vegetables is associated with a reduced abundance of sulphate‐reducing bacteria: A randomised crossover study
por: Kellingray, Lee, et al.
Publicado: (2017)

Assembling the anaerobic gamma-butyrobetaine to TMA metabolic pathway in Escherichia fergusonii and confirming its role in TMA production from dietary L-carnitine in murine models
por: Dwidar, Mohammed, et al.
Publicado: (2023)

A decrease in iron availability to human gut microbiome reduces the growth of potentially pathogenic gut bacteria; an in vitro colonic fermentation study()()
por: Parmanand, Bhavika A, et al.
Publicado: (2019)

Carnitine Requires Choline to Exert Physiological Effects in Saccharomyces cerevisiae
por: du Plessis, Michelle, et al.
Publicado: (2018)

Methodological considerations for the identification of choline and carnitine-degrading bacteria in the gut
por: Jameson, Eleanor, et al.
Publicado: (2018)

Correction: Metabolite quantification of faecal extracts from colorectal cancer patients and healthy controls
por: Le Gall, Gwénaëlle, et al.
Publicado: (2019)

Metabolite quantification of faecal extracts from colorectal cancer patients and healthy controls
por: Le Gall, Gwénaëlle, et al.
Publicado: (2018)

Urinary TMAO Levels Are Associated with the Taxonomic Composition of the Gut Microbiota and with the Choline TMA-Lyase Gene (cutC) Harbored by Enterobacteriaceae
por: Dalla Via, Alessandro, et al.
Publicado: (2019)

Berberine treats atherosclerosis via a vitamine-like effect down-regulating Choline-TMA-TMAO production pathway in gut microbiota
por: Ma, Shu-Rong, et al.
Publicado: (2022)

40S ribosome profiling reveals distinct roles for Tma20/Tma22 (MCT-1/DENR) and Tma64 (eIF2D) in 40S subunit recycling
por: Young, David J., et al.
Publicado: (2021)

APOE genotype influences the gut microbiome structure and function in humans and mice: relevance for Alzheimer’s disease pathophysiology
por: Tran, Tam T. T., et al.
Publicado: (2019)

Structural and Functional Alterations in the Microbial Community and Immunological Consequences in a Mouse Model of Antibiotic-Induced Dysbiosis
por: Shi, Ying, et al.
Publicado: (2018)

Carfilzomib-induced thrombotic microangiopathy (TMA): an under-recognised spectrum of disease from microangiopathic haemolysis to subclinical TMA
por: Ponraj, Royston, et al.
Publicado: (2023)

Translatome and transcriptome analysis of TMA20 (MCT-1) and TMA64 (eIF2D) knockout yeast strains
por: Makeeva, Desislava S., et al.
Publicado: (2019)

Pathobiological Relationship of Excessive Dietary Intake of Choline/L-Carnitine: A TMAO Precursor-Associated Aggravation in Heart Failure in Sarcopenic Patients
por: Bin-Jumah, May Nasser, et al.
Publicado: (2021)

Using XML to encode TMA DES metadata
por: Lyttleton, Oliver, et al.
Publicado: (2011)

Influence of Texture and Colour in Breast TMA Classification
por: Fernández-Carrobles, M. Milagro, et al.
Publicado: (2015)

The gene expression and bioinformatic analysis of choline trimethylamine-lyase (CutC) and its activating enzyme (CutD) for gut microbes and comparison with their TMA production levels
por: Ramireddy, Latha, et al.
Publicado: (2021)

Antibacterial Properties of TMA against Escherichia coli and Effect of Temperature and Storage Duration on TMA Content, Lysozyme Activity and Content in Eggs
por: Shi, Xuefeng, et al.
Publicado: (2022)

Carnitine in Human Muscle Bioenergetics: Can Carnitine Supplementation Improve Physical Exercise?
por: Gnoni, Antonio, et al.
Publicado: (2020)

Comparison of Different Strategies for Providing Fecal Microbiota Transplantation to Treat Patients with Recurrent Clostridium difficile Infection in Two English Hospitals: A Review
por: Goldenberg, Simon D., et al.
Publicado: (2018)

TmaDB: a repository for tissue microarray data
por: Sharma-Oates, Archana, et al.
Publicado: (2005)

Evaluation of MCM-2 Expression in TMA Cervical Specimens
por: Nicol, Alcina F., et al.
Publicado: (2012)

Reliability and Feasibility of the Memory Associative Test TMA-93
por: Franco-Macías, Emilio, et al.
Publicado: (2020)

Potential TMA-Producing Bacteria Are Ubiquitously Found in Mammalia
por: Rath, Silke, et al.
Publicado: (2020)

P1344: METHODOLOGY OF AN INTERNATIONAL MULTI-CENTER RETROSPECTIVE REVIEW OF TRANSPLANT-ASSOCIATED THROMBOTIC MICROANGIOPATHY (TA-TMA) BY THE TA-TMA WORKING GROUP
por: Ho, V., et al.
Publicado: (2022)

Microbiomes in physiology: insights into 21st‐century global medical challenges
por: Shehata, Emad, et al.
Publicado: (2022)

Lipid, fatty acid, carnitine- and choline derivative profiles in rheumatoid arthritis outpatients with different degrees of periodontal inflammation
por: Beyer, Kathrin, et al.
Publicado: (2021)

Simplified Procedure for General Synthesis of Monosubstituted Piperazines—From a Batch Reaction Vessel to a Flow (Microwave) Reactor
por: Němečková, Dana, et al.
Publicado: (2020)

Correction: Evaluation of MCM-2 Expression in TMA Cervical Specimens
por: Nicol, Alcina F., et al.
Publicado: (2012)

Progression Model Tissue Microarray (TMA) for the Study of Uterine Carcinomas
por: Arafa, Mohammad, et al.
Publicado: (2010)

Stiffness comparison of mushroom and straight SS and TMA lingual archwires
por: Lombardo, Luca, et al.
Publicado: (2016)

The Role of Complement in HSCT-TMA: Basic Science to Clinical Practice
por: Meri, Seppo, et al.
Publicado: (2022)

Concentrative Accumulation of Choline by Human Erythrocytes
por: Martin, K.
Publicado: (1968)

Choline: An Essential Nutrient for Human Health
por: Gallo, Milagros, et al.
Publicado: (2023)

Associations of Circulating Levels of Trimethylamine N-oxide, Choline, Carnitine, and Betaine with Inflammatory Markers Among Breast Cancer Survivors
por: Lee, Yeon Jin, et al.
Publicado: (2022)

Regulation of normal human polyrnorphonuclear leucocytes by carnitine
por: Fattorossi, Andrea, et al.
Publicado: (1993)

Cannot write session to /tmp/vufind_sessions/sess_b30h14si180er2bcdeoolfe6f7