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Physiological and Pathological Ageing of Astrocytes in the Human Brain

Ageing is the greatest risk factor for dementia, although physiological ageing by itself does not lead to cognitive decline. In addition to ageing, APOE ε4 is genetically the strongest risk factor for Alzheimer’s disease and is highly expressed in astrocytes. There are indications that human astrocy...

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Detalles Bibliográficos
Autores principales: Verkerke, Marloes, Hol, Elly M., Middeldorp, Jinte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437874/
https://www.ncbi.nlm.nih.gov/pubmed/33559106
http://dx.doi.org/10.1007/s11064-021-03256-7