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Therapeutic hypothermia augments the restorative effects of PKC-β and Nox2 inhibition on an in vitro model of human blood–brain barrier

To investigate whether therapeutic hypothermia augments the restorative impact of protein kinase C-β (PKC-β) and Nox2 inhibition on an in vitro model of human blood–brain barrier (BBB). Cells cultured in normoglycaemic (5.5 mM) or hyperglycaemic (25 mM, 6 to 120 h) conditions were treated with thera...

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Detalles Bibliográficos
Autores principales: Kadir, Rais Reskiawan A., Alwjwaj, Mansour, McCarthy, Zoe, Bayraktutan, Ulvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437893/
https://www.ncbi.nlm.nih.gov/pubmed/34398388
http://dx.doi.org/10.1007/s11011-021-00810-8