Chimeric antigen receptor T cells self-neutralizing IL6 storm in patients with hematologic malignancy

IL6 is one of the most elevated cytokines during chimeric antigen receptor (CAR) T cell cytokine release syndrome (CRS), and IL6R blockade by Tocilizumab has successfully relieved the most life-threatening aspects of CRS in patients. In addition, latest studies demonstrated the essential role of IL1...

Descripción completa

Detalles Bibliográficos
Autores principales: Xue, Lei, Yi, Yan, Xu, Qianwen, Wang, Li, Yang, Xiaohui, Zhang, Yongjing, Hua, Xuefei, Chai, Xiaoshan, Yang, Junjie, Chen, Yaxin, Tao, Guangshi, Hu, Biliang, Wang, Xingbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437938/
https://www.ncbi.nlm.nih.gov/pubmed/34518515
http://dx.doi.org/10.1038/s41421-021-00299-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437938/
https://www.ncbi.nlm.nih.gov/pubmed/34518515
http://dx.doi.org/10.1038/s41421-021-00299-6

Ejemplares similares