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Mesenchymal stem cells attenuate liver fibrosis by targeting Ly6C(hi/lo) macrophages through activating the cytokine-paracrine and apoptotic pathways

Mesenchymal stem cell (MSC) therapy has become a promising treatment for liver fibrosis due to its predominant immunomodulatory performance in hepatic stellate cell inhibition and fibrosis resolution. However, the cellular and molecular mechanisms underlying these processes remain limited. In the pr...

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Detalles Bibliográficos
Autores principales: Li, Yuan-hui, Shen, Shuang, Shao, Tong, Jin, Meng-ting, Fan, Dong-dong, Lin, Ai-fu, Xiang, Li-xin, Shao, Jian-zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437974/
https://www.ncbi.nlm.nih.gov/pubmed/34518510
http://dx.doi.org/10.1038/s41420-021-00584-z