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Epo/EpoR signaling in osteoprogenitor cells is essential for bone homeostasis and Epo-induced bone loss

High erythropoietin (Epo) levels are detrimental to bone health in adult organisms. Adult mice receiving high doses of Epo lose bone mass due to suppressed bone formation and increased bone resorption. In humans, high serum Epo levels are linked to fractures in elderly men. Our earlier studies indic...

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Detalles Bibliográficos
Autores principales: Rauner, Martina, Murray, Marta, Thiele, Sylvia, Watts, Deepika, Neumann, Drorit, Gabet, Yankel, Hofbauer, Lorenz C., Wielockx, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437981/
https://www.ncbi.nlm.nih.gov/pubmed/34518518
http://dx.doi.org/10.1038/s41413-021-00157-x