Cargando…
LPCAT1 reprogramming cholesterol metabolism promotes the progression of esophageal squamous cell carcinoma
Tumor cells require high levels of cholesterol for membrane biogenesis for rapid proliferation during development. Beyond the acquired cholesterol from low-density lipoprotein (LDL) taken up from circulation, tumor cells can also biosynthesize cholesterol. The molecular mechanism underlying choleste...
Autores principales: | , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438019/ https://www.ncbi.nlm.nih.gov/pubmed/34518524 http://dx.doi.org/10.1038/s41419-021-04132-6 |