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LPCAT1 reprogramming cholesterol metabolism promotes the progression of esophageal squamous cell carcinoma

Tumor cells require high levels of cholesterol for membrane biogenesis for rapid proliferation during development. Beyond the acquired cholesterol from low-density lipoprotein (LDL) taken up from circulation, tumor cells can also biosynthesize cholesterol. The molecular mechanism underlying choleste...

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Detalles Bibliográficos
Autores principales: Tao, Mingyue, Luo, Jing, Gu, Tong, Yu, Xiaojuan, Song, Zhen, Jun, Yali, Gu, Hao, Han, Kairong, Huang, Xiujuan, Yu, Weiyong, Sun, Su’an, Zhang, Zhengwei, Liu, Lu, Chen, Xiaofei, Zhang, Li, Luo, Chao, Wang, Qilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438019/
https://www.ncbi.nlm.nih.gov/pubmed/34518524
http://dx.doi.org/10.1038/s41419-021-04132-6