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CTCF knockout in zebrafish induces alterations in regulatory landscapes and developmental gene expression

Coordinated chromatin interactions between enhancers and promoters are critical for gene regulation. The architectural protein CTCF mediates chromatin looping and is enriched at the boundaries of topologically associating domains (TADs), which are sub-megabase chromatin structures. In vitro CTCF dep...

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Detalles Bibliográficos
Autores principales:	Franke, Martin, De la Calle-Mustienes, Elisa, Neto, Ana, Almuedo-Castillo, María, Irastorza-Azcarate, Ibai, Acemel, Rafael D., Tena, Juan J., Santos-Pereira, José M., Gómez-Skarmeta, José L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438036/ https://www.ncbi.nlm.nih.gov/pubmed/34518536 http://dx.doi.org/10.1038/s41467-021-25604-5

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