FBW7 couples structural integrity with functional output of primary cilia

Structural defects in primary cilia have robust effects in diverse tissues and systems. However, how disorders of ciliary length lead to functional outcomes are unknown. We examined the functional role of a ciliary length control mechanism of FBW7-mediated destruction of NDE1, in mesenchymal stem ce...

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Detalles Bibliográficos
Autores principales: Petsouki, Eleni, Gerakopoulos, Vasileios, Szeto, Nicholas, Chang, Wenhan, Humphrey, Mary Beth, Tsiokas, Leonidas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438042/
https://www.ncbi.nlm.nih.gov/pubmed/34518642
http://dx.doi.org/10.1038/s42003-021-02504-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438042/
https://www.ncbi.nlm.nih.gov/pubmed/34518642
http://dx.doi.org/10.1038/s42003-021-02504-4

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