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Composite trait Mendelian randomization reveals distinct metabolic and lifestyle consequences of differences in body shape

Obesity is a major risk factor for a wide range of cardiometabolic diseases, however the impact of specific aspects of body morphology remains poorly understood. We combined the GWAS summary statistics of fourteen anthropometric traits from UK Biobank through principal component analysis to reveal f...

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Detalles Bibliográficos
Autores principales: Sulc, Jonathan, Sonrel, Anthony, Mounier, Ninon, Auwerx, Chiara, Marouli, Eirini, Darrous, Liza, Draganski, Bogdan, Kilpeläinen, Tuomas O., Joshi, Peter, Loos, Ruth J. F., Kutalik, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438050/
https://www.ncbi.nlm.nih.gov/pubmed/34518635
http://dx.doi.org/10.1038/s42003-021-02550-y