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Composite trait Mendelian randomization reveals distinct metabolic and lifestyle consequences of differences in body shape
Obesity is a major risk factor for a wide range of cardiometabolic diseases, however the impact of specific aspects of body morphology remains poorly understood. We combined the GWAS summary statistics of fourteen anthropometric traits from UK Biobank through principal component analysis to reveal f...
Autores principales: | Sulc, Jonathan, Sonrel, Anthony, Mounier, Ninon, Auwerx, Chiara, Marouli, Eirini, Darrous, Liza, Draganski, Bogdan, Kilpeläinen, Tuomas O., Joshi, Peter, Loos, Ruth J. F., Kutalik, Zoltán |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438050/ https://www.ncbi.nlm.nih.gov/pubmed/34518635 http://dx.doi.org/10.1038/s42003-021-02550-y |
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