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Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine

Cell embedment into a solid support matrix is considered essential for the culture of intestinal epithelial organoids and tumoroids, but this technique presents challenges that impede scalable culture expansion, experimental manipulation, high-throughput screening and diagnostic applications. We hav...

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Detalles Bibliográficos
Autores principales: Hirokawa, Yumiko, Clarke, Jordan, Palmieri, Michelle, Tan, Tao, Mouradov, Dmitri, Li, Shan, Lin, Cong, Li, Fuqiang, Luo, Huijuan, Wu, Kui, Faux, Maree, Tan, Chin Wee, Lee, Margaret, Gard, Grace, Gibbs, Peter, Burgess, Antony W., Sieber, Oliver M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438070/
https://www.ncbi.nlm.nih.gov/pubmed/34518628
http://dx.doi.org/10.1038/s42003-021-02607-y