TRAPPC4 regulates the intracellular trafficking of PD-L1 and antitumor immunity

Tumor cells evade T cell-mediated immunosurveillance via the interaction between programmed death-1 (PD-1) ligand 1 (PD-L1) on tumor cells and PD-1 on T cells. Strategies disrupting PD-1/PD-L1 have shown clinical benefits in various cancers. However, the limited response rate prompts us to investiga...

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Detalles Bibliográficos
Autores principales: Ren, Yimeng, Qian, Yun, Ai, Luoyan, Xie, Yile, Gao, Yaqi, Zhuang, Ziyan, Chen, Jinxian, Chen, Ying-Xuan, Fang, Jing-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438078/
https://www.ncbi.nlm.nih.gov/pubmed/34518538
http://dx.doi.org/10.1038/s41467-021-25662-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438078/
https://www.ncbi.nlm.nih.gov/pubmed/34518538
http://dx.doi.org/10.1038/s41467-021-25662-9

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