Virulence Vs. Immunomodulation: Roles of the Paracoccin Chitinase and Carbohydrate-Binding Sites in Paracoccidioides brasiliensis Infection

Paracoccin (PCN) is a bifunctional protein primarily present in the cell wall of Paracoccidioides brasiliensis, a human pathogenic dimorphic fungus. PCN has one chitinase region and four potential lectin sites and acts as both a fungal virulence factor and an immunomodulator of the host response. Th...

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Detalles Bibliográficos
Autores principales: Pitangui, Nayla de Souza, Fernandes, Fabrício Freitas, Gonçales, Relber Aguiar, Roque-Barreira, Maria Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438136/
https://www.ncbi.nlm.nih.gov/pubmed/34532342
http://dx.doi.org/10.3389/fmolb.2021.700797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438136/
https://www.ncbi.nlm.nih.gov/pubmed/34532342
http://dx.doi.org/10.3389/fmolb.2021.700797

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