iPS Cell-Based Model for MAPT Haplotype as a Risk Factor for Human Tauopathies Identifies No Major Differences in TAU Expression

The H1 haplotype of the microtubule-associated protein tau (MAPT) gene is a common genetic risk factor for some neurodegenerative diseases such as progressive supranuclear palsy, corticobasal degeneration, and Parkinson’s disease. The molecular mechanism causing the increased risk for the named dise...

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Detalles Bibliográficos
Autores principales: Strauß, Tabea, Marvian-Tayaranian, Amir, Sadikoglou, Eldem, Dhingra, Ashutosh, Wegner, Florian, Trümbach, Dietrich, Wurst, Wolfgang, Heutink, Peter, Schwarz, Sigrid C., Höglinger, Günter U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438159/
https://www.ncbi.nlm.nih.gov/pubmed/34532319
http://dx.doi.org/10.3389/fcell.2021.726866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438159/
https://www.ncbi.nlm.nih.gov/pubmed/34532319
http://dx.doi.org/10.3389/fcell.2021.726866

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