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iPS Cell-Based Model for MAPT Haplotype as a Risk Factor for Human Tauopathies Identifies No Major Differences in TAU Expression
The H1 haplotype of the microtubule-associated protein tau (MAPT) gene is a common genetic risk factor for some neurodegenerative diseases such as progressive supranuclear palsy, corticobasal degeneration, and Parkinson’s disease. The molecular mechanism causing the increased risk for the named dise...
Autores principales: | Strauß, Tabea, Marvian-Tayaranian, Amir, Sadikoglou, Eldem, Dhingra, Ashutosh, Wegner, Florian, Trümbach, Dietrich, Wurst, Wolfgang, Heutink, Peter, Schwarz, Sigrid C., Höglinger, Günter U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438159/ https://www.ncbi.nlm.nih.gov/pubmed/34532319 http://dx.doi.org/10.3389/fcell.2021.726866 |
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