Pan-Cancer Analysis of PARP1 Alterations as Biomarkers in the Prediction of Immunotherapeutic Effects and the Association of Its Expression Levels and Immunotherapy Signatures

BACKGROUND: Poly (ADP-ribose) polymerases-1 (PARP1) alterations are associated with PARP1 inhibitor resistance, regulating the function of Treg cells and PDL1 expression in tumor cells, and high PARP1 expression is significantly associated with aggressive behavior and chemotherapeutic resistance in...

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Detalles Bibliográficos
Autores principales: Zhang, Xinke, Wang, Yingying, A, Gari, Qu, Chunhua, Chen, Jiewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438309/
https://www.ncbi.nlm.nih.gov/pubmed/34531868
http://dx.doi.org/10.3389/fimmu.2021.721030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438309/
https://www.ncbi.nlm.nih.gov/pubmed/34531868
http://dx.doi.org/10.3389/fimmu.2021.721030

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