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PD-1 Blockade on Tumor Microenvironment-Resident ILC2s Promotes TNF-α Production and Restricts Progression of Metastatic Melanoma

While pulmonary ILC2s represent one of the major tissue-resident innate lymphoid cell populations at steady state and are key drivers of cytokine secretion in their occupational niche, their role in pulmonary cancer progression remains unclear. As the programmed cell death protein-1 (PD-1) plays a m...

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Detalles Bibliográficos
Autores principales: Howard, Emily, Hurrell, Benjamin P., Helou, Doumet Georges, Quach, Christine, Painter, Jacob D., Shafiei-Jahani, Pedram, Fung, Marshall, Gill, Parkash S., Soroosh, Pejman, Sharpe, Arlene H., Akbari, Omid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438316/
https://www.ncbi.nlm.nih.gov/pubmed/34531874
http://dx.doi.org/10.3389/fimmu.2021.733136