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PD-1 Blockade on Tumor Microenvironment-Resident ILC2s Promotes TNF-α Production and Restricts Progression of Metastatic Melanoma
While pulmonary ILC2s represent one of the major tissue-resident innate lymphoid cell populations at steady state and are key drivers of cytokine secretion in their occupational niche, their role in pulmonary cancer progression remains unclear. As the programmed cell death protein-1 (PD-1) plays a m...
Autores principales: | Howard, Emily, Hurrell, Benjamin P., Helou, Doumet Georges, Quach, Christine, Painter, Jacob D., Shafiei-Jahani, Pedram, Fung, Marshall, Gill, Parkash S., Soroosh, Pejman, Sharpe, Arlene H., Akbari, Omid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438316/ https://www.ncbi.nlm.nih.gov/pubmed/34531874 http://dx.doi.org/10.3389/fimmu.2021.733136 |
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