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The Effect of JAK1/2 Inhibitors on HIV Reservoir Using Primary Lymphoid Cell Model of HIV Latency

HIV eradication is hindered by the existence of latent HIV reservoirs in CD4(+) T cells. Therapeutic strategies targeting latent cells are required to achieve a functional cure, however the study of latently infected cells from HIV infected persons is extremely challenging due to the lack of biomark...

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Detalles Bibliográficos
Autores principales: de Armas, Lesley R., Gavegnano, Christina, Pallikkuth, Suresh, Rinaldi, Stefano, Pan, Li, Battivelli, Emilie, Verdin, Eric, Younis, Ramzi T., Pahwa, Rajendra, Williams, Siôn L., Schinazi, Raymond F., Pahwa, Savita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438319/
https://www.ncbi.nlm.nih.gov/pubmed/34531866
http://dx.doi.org/10.3389/fimmu.2021.720697