Synergistic Tumor Cytolysis by NK Cells in Combination With a Pan-HDAC Inhibitor, Panobinostat

Histone deacetylases (HDAC) are frequently overexpressed in tumors, and their inhibition has shown promising anti-tumor effects. However, the synergistic effects of HDAC inhibition with immune cell therapy have not been fully explored. Natural killer (NK) cells are cytotoxic lymphocytes for anti-tum...

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Detalles Bibliográficos
Autores principales: Afolabi, Lukman O., Bi, Jiacheng, Li, Xuguang, Adeshakin, Adeleye O., Adeshakin, Funmilayo O., Wu, Haisi, Yan, Dehong, Chen, Liang, Wan, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438531/
https://www.ncbi.nlm.nih.gov/pubmed/34531855
http://dx.doi.org/10.3389/fimmu.2021.701671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438531/
https://www.ncbi.nlm.nih.gov/pubmed/34531855
http://dx.doi.org/10.3389/fimmu.2021.701671

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