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Binding Studies Reveal Phospholipid Specificity and Its Role in the Calcium-Dependent Mechanism of Action of Daptomycin

[Image: see text] Multidrug-resistant bacteria pose a serious global health threat as antibiotics are increasingly losing their clinical efficacy. A molecular level understanding of the mechanism of action of antimicrobials plays a key role in developing new agents to combat the threat of antimicrob...

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Detalles Bibliográficos
Autores principales: Kotsogianni, Ioli, Wood, Thomas M., Alexander, Francesca M., Cochrane, Stephen A., Martin, Nathaniel I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438661/
https://www.ncbi.nlm.nih.gov/pubmed/34406007
http://dx.doi.org/10.1021/acsinfecdis.1c00316