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Effect of APOE ε4 allele on levels of apolipoproteins E, J, and D, and redox signature in circulating extracellular vesicles from cognitively impaired with no dementia participants converted to Alzheimer's disease

INTRODUCTION: The substantial link between apolipoprotein E (APOE) ε4 allele and oxidative stress may underlie enhanced Alzheimer's disease (AD) risk. Here, we studied the impact of APOE ε4 on the level of apolipoproteins with antioxidant activities along with oxidative markers in circulating e...

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Detalles Bibliográficos
Autores principales: Ben Khedher, Mohamed Raâfet, Haddad, Mohamed, Laurin, Danielle, Ramassamy, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438681/
https://www.ncbi.nlm.nih.gov/pubmed/34541286
http://dx.doi.org/10.1002/dad2.12231