Functional analysis of peripheral and intratumoral neoantigen-specific TCRs identified in a patient with melanoma

BACKGROUND: Neoantigens derived from somatic mutations correlate with therapeutic responses mediated by treatment with immune checkpoint inhibitors. Neoantigens are therefore highly attractive targets for the development of therapeutic approaches in personalized medicine, although many aspects of th...

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Detalles Bibliográficos
Autores principales: Bräunlein, Eva, Lupoli, Gaia, Füchsl, Franziska, Abualrous, Esam T, de Andrade Krätzig, Niklas, Gosmann, Dario, Wietbrock, Lukas, Lange, Sebastian, Engleitner, Thomas, Lan, Huan, Audehm, Stefan, Effenberger, Manuel, Boxberg, Melanie, Steiger, Katja, Chang, Yinshui, Yu, Kai, Atay, Cigdem, Bassermann, Florian, Weichert, Wilko, Busch, Dirk H, Rad, Roland, Freund, Christian, Antes, Iris, Krackhardt, Angela M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438848/
https://www.ncbi.nlm.nih.gov/pubmed/34518289
http://dx.doi.org/10.1136/jitc-2021-002754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438848/
https://www.ncbi.nlm.nih.gov/pubmed/34518289
http://dx.doi.org/10.1136/jitc-2021-002754

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