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miR-146a-5p-mediated suppression on trophoblast cell progression and epithelial-mesenchymal transition in preeclampsia

OBJECTIVE: This study aims to identify the effect of miR-146a-5p on trophoblast cell invasion as well as the mechanism in preeclampsia (PE). METHODS: Expression levels of miR-146a-5p and Wnt2 in preeclamptic and normal placentae were quantified. Trophoblast cells (HTR-8) were separately transfected...

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Detalles Bibliográficos
Autores principales: Peng, Pingping, Song, Huamei, Xie, Chenghong, Zheng, Wenfei, Ma, Huigai, Xin, Dandan, Zhan, Jingqiong, Yuan, Xiaoqing, Chen, Aihua, Tao, Jing, Qin, Jufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438983/
https://www.ncbi.nlm.nih.gov/pubmed/34517910
http://dx.doi.org/10.1186/s40659-021-00351-5